Lipid Interaction Networks of Peripheral Membrane Proteins Revealed by Data-Driven Micelle Docking
نویسندگان
چکیده
منابع مشابه
Interaction of membrane-spanning proteins with peripheral and lipid-anchored membrane proteins: perspectives from protein-lipid interactions (Review).
Studies of lipid-protein interactions in double-reconstituted systems involving both integral and peripheral or lipid-anchored proteins are reviewed. Membranes of dimyristoyl phosphatidylglycerol containing either myelin proteolipid protein or cytochrome c oxidase were studied. The partner peripheral proteins bound to these membranes were myelin basic protein or cytochrome c, respectively. In a...
متن کاملInteraction of membrane skeletal proteins with membrane lipid domain.
The object of this paper is to review briefly the studies on the interaction of red blood cell membrane skeletal proteins and their non-erythroid analogues with lipids in model systems as well as in natural membranes. An important question to be addressed is the physiological significance and possible regulatory molecular mechanisms in which these interactions are engaged.
متن کاملEvolutionary Docking of Proteins - Computational prediction of functional interaction networks
The coupled evolution of pairs of positions is the cornerstone in the prediction of RNA secondary structure (Knudsen and Hein, 1999) and thus the position of RNA genes in DNA sequences. There have been similar attempts to use such dependencies to predict which protein residues were physically close (Abe and Mamitsuka, 1993; Chiang et al. 2006, Pollock et al., 1999; Bickel et al., 2002). However...
متن کاملInteraction of aldehydes derived from lipid peroxidation and membrane proteins
A great variety of compounds are formed during lipid peroxidation of polyunsaturated fatty acids of membrane phospholipids. Among them, bioactive aldehydes, such as 4-hydroxyalkenals, malondialdehyde (MDA) and acrolein, have received particular attention since they have been considered as toxic messengers that can propagate and amplify oxidative injury. In the 4-hydroxyalkenal class, 4-hydroxy-...
متن کاملMinimal membrane docking requirements revealed by reconstitution of Rab GTPase-dependent membrane fusion from purified components.
Rab GTPases and their effectors mediate docking, the initial contact of intracellular membranes preceding bilayer fusion. However, it has been unclear whether Rab proteins and effectors are sufficient for intermembrane interactions. We have recently reported reconstituted membrane fusion that requires yeast vacuolar SNAREs, lipids, and the homotypic fusion and vacuole protein sorting (HOPS)/cla...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2008
ISSN: 0006-3495
DOI: 10.1529/biophysj.107.115923